[Effects of different levels of zeolite on plant growth and amount of gel production in Aloe vera L. under different irrigation]

Researchers' attention has been focused on Aloe vera for a long time due to the numerous medicinal effects of this plant and its application in various fields of food, cosmetic and hygienic industries. This study was conducted to evaluate the different levels of Zeolite and irrigation conditions on vegetative growth and quantitative and qualitative changes in plant gel. It is based on a factorial randomized complete block design with 4 levels of Zeolite in soil and 3 levels of irrigation, in 3 replications. After 5 months, morphological traits were measured. Also the amount of aloin in leaf and vitamin C in the gel were measured. The best results of morphological traits were obtained with 22 g Zeolite treatment in 5 kg pots of soil and 21 days irrigation. The highest amount of aloin was observed in 44 g Zeolite treatment in 5 kg pots of soil with 7 days irrigation. The highest amount of vitamin C was obtained in 44 g Zeolite treatment in 5 kg pots of soil with 14 days irrigation. The overall results showed that zeolite plays an important role in promoting growth and increasing secondary metabolites in plant Aloe vera under different irrigation

[Separation and calibration of some anthraquinones in the types of aloe which grow in Syria]

Aloe is one of the most important medicinal plants at the present time, which entered to Syria since a long time. Genus Aloe has about four hundred species. In this research species in Syria were classified, which their number is six. Aloin and Aloe-emodin were calibrate in the six species that are the most important Anthraquinones. It was noted that there is not Aloe-emodin in the six species, but there is Aloin only in five types

Inhibition of azoxymethane-induced DNA adduct formation by Aloe arborescens var. natalensis.

To clarify the possible mechanisms of inhibition of azoxymethane (AOM)-induced aberrant crypt foci (ACF) in the rat colorectum by freeze-dried whole leaves of Aloe arborescens var. natalensis (Kidachi aloe) (hereinafter referred to as ALOE) and commercial crude aloin (Sigma A-0451; from Curacao aloe) (hereinafter ALOIN), we studied the effects of ALOE and ALOIN on the formation of AOM-induced DNA adducts (O6-methylguanine; O6-MeG) in rats. Male F344 rats (4 weeks old) were fed a basal diet, or experimental diets containing 5%ALOE or 0.25%ALOIN for 5 weeks. All rats were injected s.c. twice with 15 mg/kg AOM, once at the end of week 1, and once at the end of week 2. The animals were sacrificed 6 hours after the second injection to analyze DNA adducts (O6-MeG) in the colorectum. Dietary administration of ALOE significantly inhibited the O6-MeG levels (50% reduction) compared with controls, whereas the O6-MeG levels in the ALOIN-fed rats showed a tendency to decrease (by 30%), although not significantly. In this study, we also measured the enzyme activity and mRNA level of cytochrome (CYP) 2E1, known to be responsible for the activation of AOM, in rat liver. ALOE-fed rats showed significantly reduced CYP2E1 enzymatic activity (27% reduction) compared with controls. On the other hand, the activity in ALOIN-fed rats tended to decrease by 11%, although not significantly. The CYP2E1 mRNA levels in ALOE- and ALOIN-fed rats were slightly reduced (9.7% and 5.2%, respectively). These results may explain, at least in part, the previously observed inhibitory effects of ALOE and ALOIN, especially ALOE on AOM-induced ACF formation in the rat colorectum.